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The ACC document, which was endorsed by the American Diabetes Association (ADA), outlined a variety of considerations for use of these agents in patients with ASCVD, including considerations that may warrant selection of either a GLP-1 RA or an SGLT-2 inhibitor for cardiovascular risk reduction ( Table 1 )

Curcumin, psyllium, cinnamon, and ginseng each have human RCT evidence supporting their metabolic effects

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For exercise, they kept it simple walking 2-3 miles a day and adding more general movement into their daily routine